After a human sperm fuses with an ovum to form a zygote, this zygote inherits the genetic characteristics from the parents. These include the appearances, such as height, hair color, skin color, and eye color; the I.Q., which display one’s own faculties, and the innate talent, such as music and art as well as the inherited defects, i.e., genetic diseases that lead the body to illness.

There are many factors, including single-gene defects, chromosomal abnormalities, the joint effects of multiple genes, and mutations of mitochondrial DNA, which can cause genetic diseases as listed below:

Favsim (Glucose-6-phosphate dehydrogenase deficiency, G6PD deficiency): a deficiency in G6PD enzyme activity will induce the risk of developing hemolysis when eating fava beans, or taking quinine pharmaceuticals.
Cystic Fibrosis: protein abnormalities that lead to thick mucus accumulating in lungs or other parts of the body.
Phenylketonuria: impaired metabolism of phenylalanine hydroxylase that causes brain development disorders.
Alpha-1 antitrypsin deficiency, AAT deficiency: In the process of white blood cells destroying invading bacteria, normal protein can inhibit the enzyme released from white blood cells. Patients with this disease cannot inhibit the release of the enzyme, which leads to pulmonary emphysema.
Sickle Cell Anemia: sickle-shaped red blood cells that carry abnormal hemoglobin can cause hemolysis in capillaries which have lower dissolved oxygen.
Adenosine deaminase deficiency, ADA deficiency: such deficiency affects the normal functioning of lymphocytes and the immune system.
Duchenne muscular dystrophy: due to the existence of abnormal muscular protein, the muscles of the patients will be gradually degenerated and even the muscles essential for respiration will also lose functions.
Hemophilia A:  caused by a defect in the protein, functional plasma clotting factor VIII, an essential factor for blood clotting.
Tay-Sachs disease: due to an enzyme abnormality in decomposing a cell membrane lipid, abnormal fragments of the cell membrane gradually accumulate, leading to deterioration of the nervous system.
Color blindness: as a sex-linked genetic recessive disease, the patient is completely unable to distinguish colors, usually accompanied by other problems with eyes, such as amblyopia, nystagmus, photosensitivity reactions, and extremely poor eyesight.
Familial hypercholesterolemia, FHC: such genetic disorder affects absorption of cholesterol and increases the risk of developing angiosclerosis and coronary artery disease.
Huntington’s disease: a neurodegenerative genetic disorder
X-linked hypophosphatemic rickets: a mutation in PHEX protein in the kidneys lead to low concentration of phosphate in the bloodstream, inducing chronic stimulation of parathyroid hormone to the bones to release calcium ion and phosphate, which causes fragile bones and deformity.
Thalassemia: such genetic disorder will affect the decrease or deficiency in the amount of hemoglobin synthesis in red blood cells.
Down’s syndrome: unbalanced copy of chromosome 21 causes mild or even serious intellectual disabilities and several kinds of physical changes.

In the latest researches, almost all the diseases occurring  in the cell, tissue, organ, and system of the human body, such as coronary heart disease, high blood pressure, stroke, diabetes, and cancer, etc. as well as mutations of mitochondrial genes, are associated with genetic disorders.

The DNA sequences in the reproductive cells of the New Human Line have the capacity to modify genetic defects through free shifting.  When genes go through transcription and translation process, this capacity can repair severely-damaged DNA sequences through free forward and backward shifting to keep genes in normal condition.